The DHL Stormers lock Moerat and the Vodacom Bulls No.8 Louw, both beginning on the seat in areas of strength for a side.
Elton Jantjies begins at flyhalf in Handre Pollard's nonattendance after winning the Top 14 with Montpellier on Saturday. Franco Mostert starts in the No.7 pullover after Pieter-Steph du Toit was managed out of this Test. At the same time, Jasper Wiese begins at No.8, beating United Rugby Championship Player of the Season Evan Roos in the competition to be chosen.
It is additionally the recognizable 6-2 split on the seat, with Herschel Jantjies and Willie le Roux taking the two backspaces, while the adaptable Damian Willemse begins at fullback.
"We have a capable gathering of players, and we accept the matchday crew we chose marks the crates as far as what we might want to accomplish in the initial Test against Wales," said Nienaber.
"We enjoy the additional benefit of having a few very flexible players, so a person like Damian Willemse, for instance, can cover flyhalf and focus notwithstanding fullback, while Kwagga covers every free forward position and might opening in at wing with his Blitzbok experience.
"Franco likewise gives us choices at free forward and lock, so we anticipate seeing what this group can deliver on Saturday."
On the choice of Moerat and Louw, Nienaber said: "We have a great harvest of youthful players who have truly been taking a stab at preparing and setting up their hands, and it is satisfying as far as we're concerned as mentors to offer Salmaan and Elrigh this chance.
"Salmaan was with us on our visit to the UK last season, and regardless of being so youthful, he brings an alternate feeling of involvement as a previous Junior Springbok and SA Schools commander, while Elrigh likewise highlighted in a World Rugby U20 Championship and has been playing commonplace senior rugby for some time.
15 - Damian Willemse (DHL Stormers)
14 - Cheslin Kolbe (Toulon)
13 - Lukhanyo Am (Cell C Sharks)
12 - Damian de Allende (Munster)
11 - Makazole Mapimpi (Cell C Sharks)
10 - Elton Jantjies (NTT Docomo Red Hurricanes)
9 - Faf de Klerk (Yokohama Canon Eagles)
8 - Jasper Wiese (Leicester Tigers)
7 - Franco Mostert (Honda Heat)
6 - Siya Kolisi (skipper, Cell C Sharks)
5 - Lood de Jager (Panasonic Wild Knights)
4 - Eben Etzebeth (Cell C Sharks)
3 - Frans Malherbe (DHL Stormers)
2 - Bongi Mbonambi (Cell C Sharks)
1 - Ox Nché (Cell C Sharks)
16 - Malcolm Marx (Kubota Spears)
17 - Steven Kitshoff (DHL Stormers)
18 - Vincent Koch (Wasps)
19 - Salmaan Moerat (DHL Stormers)
20 - Elrigh Louw (Vodacom Bulls)
21 - Kwagga Smith (Yamaha Júbilo)
22 - Herschel Jantjies (DHL Stormers)
23 - Willie le Roux (Toyota Verblitz)
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